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What Biofabrication Means for the Future of Business

In labs around the world, a quiet revolution is taking place. Instead of building with plastic, steel, or silicon,

What Biofabrication Means for the Future of Business

In labs around the world, a quiet revolution is taking place. Instead of building with plastic, steel, or silicon, scientists and startups are using living cells as their raw materials. This new frontier, called biofabrication, is shaping the future of medicine, fashion, food, and manufacturing.

What Is Biofabrication?

Biofabrication is the automated production of biological structures using techniques like 3D bioprinting, bioassembly, and cell-based manufacturing. Unlike traditional manufacturing, which relies on synthetic materials, biofabrication builds with biological components such as living cells, proteins, and biomaterials.

To understand how this works, picture a 3D printer. Rather than using ink or plastic, this machine prints layers of living tissue. This concept, known as bioprinting, allows scientists to create tissues and structures that replicate the function of human organs.

From Lab to Market: Where Biofabrication Is Already Making Waves

Regenerative Medicine

One of the most developed applications of biofabrication is in regenerative medicine. For example, researchers are developing lab-grown skin, cartilage, blood vessels, and other tissue types that may soon be used in surgeries or organ transplants. In some hospitals, bioprinted skin grafts are currently undergoing clinical testing for burn victims.

Lab-Grown Meat

Biofabrication also extends beyond human medicine. Several startups are growing real meat in bioreactors without involving animals. By culturing animal cells and layering them into tissue-like structures, these companies are creating burgers, steaks, and even fish fillets. The goal is to build a cleaner, more ethical food supply.

Sustainable Fashion

Fashion is another industry experimenting with biofabrication. Designers and material scientists are exploring lab-grown leather, mycelium-based fabrics (derived from fungi), and even sequins produced by bacteria. These materials decompose naturally and consume far fewer resources than traditional textiles.

Consumer Products

Moreover, the same processes used to grow tissue can create high-performance materials. Some companies are developing biofabricated alternatives to plastics, cosmetics, and architectural products.

Why It Matters for Business

The potential of biofabrication stretches far beyond science fiction. It marks a shift in how products are made, who produces them, and what they’re made of. For business owners and investors, biofabrication offers:

  • New markets: Including cultured meat and custom-grown medical implants
  • Reduced environmental impact: With less waste, fewer toxic chemicals, and lower water usage
  • Premium branding opportunities: Ethical, sustainable products that appeal to modern consumers
  • Vertical integration: Businesses can manage biological production internally

The Challenges Ahead

Despite its promise, biofabrication still faces obstacles. These include:

  • Scaling: Companies must find ways to grow living materials consistently and affordably
  • Regulation: New legal frameworks are required for bioengineered food, medicine, and consumer goods
  • Public perception: Businesses must address the “ick factor” associated with lab-grown products
  • Ethics: Important questions remain about synthetic life and biological patents

Who’s Leading the Charge in Biofabrication?

Who's leading the charge in biofabrication

Several startups and research institutions are shaping this emerging field:

  • Modern Meadow: Focused on lab-grown leather and biofabricated materials
  • Upside Foods: Among the first to produce cultured meat for consumers
  • Cellink: A bioprinting company contributing to skin, bone, and cancer research
  • MIT and Harvard: Both universities are advancing the science of tissue engineering

What Comes Next

As methods improve and awareness grows, biofabrication is likely to become central to the next industrial revolution. New applications could include:

  • Organ printing: Producing fully functional organs for transplant
  • Drug testing platforms: Replacing animal testing with human tissue models
  • Smart materials: Developing products that grow, self-heal, or respond to the environment

Rethinking the Raw Material of the Future

Biofabrication encourages us to reconsider the origin of our products. Instead of relying on traditional chemistry, it uses biology to create items with minimal waste and greater precision.

Forward-thinking founders and investors should take notice. The factories of tomorrow may not clang with steel and machinery. Instead, they may pulse with life—powered by cells, science, and imagination.


Ex Nihilo is a magazine for entrepreneurs and startups, connecting them with investors and fueling the global entrepreneur movement

About Author

Chris Duran

Chris Duran is a content specialist of EX NIHILO Magazine and TDS Australia.

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